antibiotic susceptibility and resistance patterns of pseudomonas aeruginosa strains isolated from different clinical specimens in patients referred to the teaching hospitals in kermanshah(2001-2)

background& objectives :    pseudomonas aeruginosa is inherently resistant to many antibiotics at concentrations that can be achieved in vivo. this study was done to assess the susceptibility of p.aeruginosa strains, isolated from kermanshahian patients, to the most commonly prescribed  antibiotics.  materials and methods : 50 clinical specimens collected and examined from july 2001 to july 2002 from three hospitals(sina, imam khomeini, taleghani).   mic90 was determined by sigma powders and agar dilution method for the following antibiotics:amikacin,azlocillin,aztreonam,carbenicillin,ceftazidime,ciprofloxacin, gentamicin, imipenem, mezlocillin, norfloxacin, ticarcillin and tobramycin.  results: resistance to amikacin, azlocillin, aztreonam, carbenicillin, ceftazidime, ciprofloxacin, gentamicin, imipenem, mezlocillin, norfloxacin, ticarcillin and tobramycin was 38%, 52%, 80% ,72%, 50%, 38%, 52%, 10%, 98%, 40%, 90% and 46%, respectively.  discussion : there is no significant difference between our results and others' studies. imipenem was the most effective antibiotic against p.aeruginosa strains isolated from our patients.